We study how microtubule networks are regulated to drive different processes in cells. Our primary model system is the budding yeast, Saccharomyces cerevisiae, which affords powerful genetics that we combine with quantitative microscopy and protein biochemistry to investigate basic molecular mechanisms that regulate dynamics and transport. Our goals are to build an understanding of how the microtubule network organizes the cell, how these processes are tuned for different contexts, and how defects in network function contribute to human disease.
Colby and Cassi's methods paper entitled "High-Resolution Imaging and Analysis of Individual Astral Microtubule Dynamics in Budding Yeast" in now in press at Journal of Visualized Experiments. Movie coming soon...
12/7/16 Moore Lab at ASCB
We presented five posters at the annual meeting of the American Society for Cell Biology in San Francisco.
12/1/16 NSF CAREER Grant Awarded
We are excited to begin a new project entitled
"Elucidating the Mechanism of Microtubule Dynamics through Cold-stable Tubulin Mutants". This project includes an integrated research-teaching partnership with Denver Public Schools.
10/30/16 Congrats Colby!
Colby wins a presentation award for his poster at the annual retreat of the Graduate Program in Molecular Biology.
10/15/16 Congratulations Jayne!
Jayne wins a presentation award for her poster at the annual retreat of the Graduate Program in Cell Biology, Stem Cells and Development.